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The most popular medicine in the U.S. was prescribed 128 million times last year, even as a panel of experts called together by the Food and Drug Administration recommended that regulators ban it.
The drug is Vicodin, a 40-year-old addictive medicine that combines the narcotic hydrocodone with acetaminophen, the active ingredient in Tylenol; the prescription tally also includes numerous generic versions. It is emblematic of the trend that emerges from our look at the most popular prescription pills: the death of the blockbuster drug.
http://www.forbes.com/2010/05/11/narcotic-painkiller-vicodin-business-healthcare-popular-drugs.html